A subgroup of mitochondrial extracellular vesicles discovered in human melanoma tissues are detectable in patient blood

Su Chul Jang, Rossella Crescitelli, Aleksander Cvjetkovic, Valerio Belgrano, Roger Olofsson Bagge, Johanna L. Höög, Karin Sundfeldt, Takahiro Ochiya, Raghu Kalluri, Jan Lötvall Krefting Research Center, Institute of Medicine, University of Gothenburg, Gothenburg 405 30, Sweden; Codiak BioSciences Inc., Cambridge, MA 02139, USA; Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, Gothenburg 413 45, Sweden; Department of Chemistry and Molecular Biology, Faculty of Natural Sciences, University of Gothenburg, Gothenburg 405 30, Sweden; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Cancer Center, University of Gothenburg, Gothenburg 405 30, Sweden; Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Tokyo 104-0045, Japan; Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, Texas 77005, USA